Updated GamaSTAN® S/D Indications & Hepatitis A Outbreaks

Date: July 28, 2017

Grifols has made some important changes to the prescribing information for GamaSTAN® S/D. The following are dosing instruction changes for the hepatitis A pre and post exposure prophylaxis indication.

  • GamaSTAN S/D in a dose of 0.05 mL/lb (0.1 mL/kg) is recommended for household and institutional hepatitis A case contacts.
  • The following doses of GamaSTAN S/D are recommended for persons who plan to travel in areas where hepatitis A is common.
Length of Stay Dose Volume
Up to 1 month 0.1 mL/kg
Up to 2 months 0.2 mL/kg
2 months or longer Repeat dose of 0.2 mL/kg every two months

This dosage change is based on lower concentrations of anti-hepatitis A virus (HAV) due to the decreasing prevalence of previous HAV infection among plasma donors.

To learn more about the revised dosage instructions for GamaSTAN® S/D, please read here.

Hepatitis A Outbreaks

Earlier this month, the California Department of Public Health issued a health advisory regarding outbreaks of hepatitis A. This advisory is directed at healthcare providers and care centers that provide services to homeless people or persons using illicit drugs. As a reminder, the hepatitis A vaccine is also routinely recommended for the following groups:

  • persons with chronic liver disease, including those with hepatitis B or C virus infection
  • users of injection and noninjection illicit drugs
  • men who have sex with men
  • persons traveling to or working in countries that have high or intermediate levels of HAV transmission
  • children, starting at age 1 year
  • any person wishing to obtain immunity to HAV

To learn more about the hepatitis A outbreaks, please read here.