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Monday, March 21, 2022
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Influenza Vaccines Offer Meager Protection Against Circulating Strains


In this Issue

•  IVIG/Albumin Supply Index
•  Open Market Pricing
•  New Products from FFF
•  Current Medicare
•  Resources
•  Subscribe to IG Living and BioSupply Trends Quarterly
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According to the Centers for Disease Control and Prevention, this season's flu vaccine offered meager protection against mild cases of influenza. Against the most common flu strain circulating, the flu shot reduced a person's chance of getting a mild case by 16 percent, which is "essentially ineffective," although the vaccines "should offer some protection against more severe illness." read more ]

New Vaccine Provides Strong Protection Against COVID-19

A late-stage clinical study evaluating a new Sanofi and GSK vaccine called Vidprevtyn, a protein subunit vaccine that uses harmless protein fragments to teach the immune system how to spot and fight off the SARS-CoV-2 virus, found that after two doses given to people with no antibodies against the SARS-CoV-2 virus, the vaccine was 58 percent effective at preventing COVID-19 symptoms, 75 percent effective at preventing moderate or severe COVID-19 and 100 percent effective against severe COVID-19 disease, including hospitalizations. read more ]

Study Finds Most mRNA COVID-19 Vaccine Side Effects Were Mild

A new study that looked at data from more than seven million self-reported instances of negative side effects from mRNA vaccine doses administered between December 2020 and June 2021 found most side effects from mRNA COVID-19 vaccines were mild and faded substantially after one day. Pain at the site of injection, fatigue and headache were the most commonly reported negative side effects. read more ]

IG Treatment May Reduce Acute Exacerbations of COPD

Observational studies suggest immune globulin (IG) treatment may reduce the frequency of acute exacerbations of chronic obstructive pulmonary disease (CODP). read more ]

Industry News

Industry News Image

From Moderna and Novovax

Moderna and Novovax have announced plans to work on a combination COVID-19 and influenza vaccine that they hope will be ready by 2023. read more ]

From Pfizer

Pfizer plans to submit data to the U.S. Food and Drug Administration for a fourth COVID-19 vaccine, and it's working on a vaccine that protects against all coronavirus variants, according to CEO Albert Bourla. read more ]

From Novartis

Novartis has received U.S. Food and Drug Administration (FDA) approval for its Cosentyx (secukinumab) to treat children and adolescents with enthesitis-related arthritis and psoriatic arthritis. read more ]

From Argenx

The U.S. Food and Drug Administration has approved Vyvgart (efgartigimod) to treat generalized myasthenia gravis in adults who test positive for the anti-acetylcholine receptor (AChR) antibody. read more ]

IVIG & Albumin Supply Index

IVIG and Albumin Days On Hand

What's New at FFF


VAZCULEP (phenylephrine hydrochloride) injection is an alpha-1 adrenergic receptor agonist indicated for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia. It is supplied in a strength of 10 mg/mL in a 1 mL single-use vial in packages of 10, a 5 mL vial in packages of 10 and a 10 mL vial as a single unit.

For more information about VAZCULEP, log in to


TRANEXAMIC ACID in sodium chloride injection is indicated in patients with hemophilia for short-term use (i.e., 2-8 days) to reduce/prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction. It is supplied as a sterile, unpreserved, colorless solution in a single-dose polymeric bag containing 1,000 mg tranexamic acid in 100 mL of solution (10 mg/mL) sealed with a twist-off port and oversealed in an aluminum pouch.

For more information about TRANEXAMIC ACID, log in to


GLYRX-PF is an anticholinergic indicated in 1) anesthesia (adult and pediatric patients) for reduction of airway or gastric secretions, and volume and acidity of gastric secretions, and blockade of cardiac inhibitory reflexes during induction of anesthesia and intubation; intraoperatively to counteract surgically or drug-induced or vagal reflex-associated arrhythmias; and for protection against peripheral muscarinic effects of cholinergic agents; and 2) in peptic ulcer (adults) as adjunctive therapy for the treatment of peptic ulcer when rapid anticholinergic effect is desired or oral medication is not tolerated. It is supplied in 1 mL single-dose (0.2 mg/mL) vials packaged in 25s and 2 mL single-dose (0.4 mg/2 mL) vials packaged in 25s.

For more information about GLYRX-PF, log in to


CAFFEINE CITRATE ORAL SOLUTION is indicated for the short-term treatment of apnea of prematurity in infants between 28 and <33 weeks gestational age. It is supplied as a clear, color¬less, sterile, non-pyrogenic, preservative-free, aqueous solution in 5 mL colorless glass vials containing 3 mL solution at a concentration of 20 mg/mL caffeine citrate (60 mg/vial) equivalent to 10 mg/mL caffeine base (30 mg/vial).

For more information about CAFFEINE CITRATE ORAL SOLUTION, log in to


VERAPAMIL is indicated for the treatment of supraventricular tachyarrhythmias, including 1) Rapid conversion to sinus rhythm of paroxysmal supraventricular tachycardias, including those associated with accessory bypass tracts (Wolff-Parkinson-White [WPW] and Lown-Ganong-Levine [LGL] syndromes); and 2) temporary control of rapid ventricular rate in atrial flutter or atrial fibrillation, except when the atrial flutter and/or atrial fibrillation are associated with accessory bypass tracts (WPW and LGL syndromes). It is supplied in 5 mg (2 mL) vials in a carton of five; 5 mg (2 mL) vials in a carton of 25; and 10 mg (4 mL) vials in a carton of five.

For more information about VERAPAMIL, log in to


NIPRIDE RTU sodium nitroprusside injection is a direct acting vasodilator indicated for immediate reduction of blood pressure; producing controlled hypotension to reduce bleeding during surgery; and treatment of acute heart failure to reduce left ventricular end-diastolic pressure, pulmonary capillary wedge pressure, peripheral vascular resistance and mean arterial blood pressure. It is supplied in amber-colored, single-dose, 50 mg/100 mL (0.5 mg/mL) fliptop vials, 20 mg/100 mL (0.2 mg/mL) fliptop vials and 10 mg/50 mL (0.2 mg/mL) fliptop vials.

For more information about NIPRIDE RTU, log in to


METHYLENE BLUE injection is used to treat methemoglobinemia (a blood disorder in which an abnormal amount of methemoglobin is produced). It is supplied in 10 mL single-dose vials.

For more information about METHYLENE BLUE, log in to


LANREOTIDE injection is a somatostatin analog indicated for 1) the long-term treatment of acromegalic patients who have had an inadequate response to or cannot be treated with surgery and/or radiotherapy; and 2) the treatment of adult patients with unresectable, well or moderately differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors to improve progression-free survival. It is supplied in strengths of 60 mg/0.2 mL, 90 mg/0.3 mL and 120 mg/0.5 mL in single-dose prefilled syringes.

For more information about LANREOTIDE, log in to


ABLYSINOL (dehydrated alcohol) injection is an ablative agent indicated to induce controlled cardiac septal infarction to improve exercise capacity in adults with symptomatic hypertrophic obstructive cardiomyopathy who are not candidates for surgical myectomy. It is supplied in 1 mL and 5 mL clear, glass, single-dose ampules.

For more information about ABLYSINOL, log in to


FOSFOMYCIN TROMETHAMINE is indicated only for the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis. It is not indicated for the treatment of pyelonephritis or perinephric abscess. It is supplied in a 3 gram single-dose sachet.

For more information about FOSFOMYCIN TROMETHAMINE, log in to


TICOVAC is an intramuscular vaccine indicated for active immunization to prevent tick-borne encephalitis in individuals 1 year of age and older. It is supplied in 0.25 mL and 0.5 mL pre-filled syringes in one dose or in packages of 10.

For more information about TICOVAC, log in to


FENTANYL CITRATE injection is indicated for 1) analgesic action of short duration during the anesthetic periods, premedication, induction and maintenance, and in the immediate postoperative period (recovery room) as the need arises; 2) use as an opioid analgesic supplement in general or regional anesthesia; 3) administration with a neuroleptic as an anesthetic premedication for the induction of anesthesia and as an adjunct in the maintenance of general and regional anesthesia and 4) use as an anesthetic agent with oxygen in selected high-risk patients such as those undergoing open heart surgery or certain complicated neurological or orthopedic procedures. It is supplied in single-dose ampules of 100 mcg Fentanyl/2 mL, 250 mcg Fentalyl/5 mL, 500 mcg Fentanyl/10 mL and 1000 mcg Fentanyl/20 mL, as well as in trays of 25 containing 2 mL, 5 mL, 10 mL, 20 mL and 50 mL single-dose fliptop vials.

For more information about FENTANYL CITRATE, log in to


SENSORCAINE (bupivacaine HCl) is indicated for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. It is supplied in 10 mL (2.5 mg/mL, 5 mg/mL and 7.5 mg/mL) and 30 mL (2.5 mg/mL and 5 mg/mL) single-dose vials in trays of 25, as well as 30 mL (2.5 mg/mL and 5 mg/mL) single-dose vials packaged in 5.

For more information about SENSORCAINE, log in to


ADAPALENE AND BENZOYL PEROXIDE GEL 0.3%/2.5% is a combination of adapalene, a retinoid, and benzoyl peroxide indicated for the topical treatment of acne vulgaris. It is supplied in a 45 gram pump.

For more information about ADAPALENE AND BENZOYL PEROXIDE GEL, log in to


ALBUTEIN 5% (human) is an albumin solution indicated for hypovolemia, cardiopulmonary bypass procedures, hypoalbuminemia and plasma exchange. It is supplied in an easy-to-use, flexible container.

For more information about ALBUTEIN FLEXBAG 5%, log in to


PYRIMETHAMINE TABLETS 25 mg are indicated for the treatment of toxoplasmosis when used conjointly with a sulfonamide, since synergism exists with this combination. They are supplied as tablets, each containing 25 mg pyrimethamine in bottles of 100 (NDC 47781-925-01) and 30 (NDC 47781-925-30) and in 30-count unit-dose blister cartons (NDC 47781-925-31).

For more information about PYRIMETHAMINE TABLETS, log in to


ACETAMINOPHEN INJECTION is indicated for the management of mild to moderate pain in adult and pediatric patients 2 years and older; management of moderate to severe pain with adjunctive opioid analgesics in adult and pediatric patients 2 years and older; and reduction of fever in adult and pediatric patients. It is a clear colorless solution supplied sterile and nonpyrogenic in 50 mL and 100 mL fill PAB containers packaged 24 per case.

For more information about ACETAMINOPHEN INJECTION, log in to


VAXELIS is a three-dose vaccine indicated for active immunization to prevent diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B and invasive disease due to Haemophilus influenzae type b in children 6 weeks through 4 years old. It is supplied in a single-dose vial in packages of 10 and a 0.5 mL single-dose prefilled syringe with a Luer lock connection and a tip cap without a needle in packages of 10.

For more information about VAXELIS, log in to

These products can be ordered from FFF Enterprise's BioSupply Online Ordering System or by calling
Wow! Customer Care at (800) 843-7477.

Current Medicare IVIG / SCIG Rates

Rates per gram are effective January 1, 2022, through March 31, 2022.

Calculate Your Current Medicare IVIG/SCIG Rates
Product J Codes ASP + 6%
(before sequester)
ASP + 4.3%*
(after sequester)
ASCENIV J1554 $963.54 $948.09
BIVIGAM J1556 $140.89 $138.72
FLEBOGAMMA DIF J1572 $71.79 $70.63
GAMMAGARD SD J1566 $139.18 $136.95
GAMMAPLEX J1557 $101.61 $99.98
OCTAGAM J1568 $83.23 $81.89
PANZYGA 90283 / J1599 $130.09 $128.01
PRIVIGEN J1459 $90.02 $88.57
CUTAQUIG 90284 / J3590 $135.26 $133.09
CUVITRU J1555 $147.48 $145.11
HIZENTRA J1559 $117.85 $115.96
HYQVIA J1575 $154.19 $151.72
XEMBIFY J1558 $132.96 $130.83
GAMMAGARD LIQUID J1569 $93.33 $91.84
GAMMAKED J1561 $93.02 $91.53
GAMUNEX-C J1561 $93.02 $91.53

* Reflects 2% sequestration reduction applied to 80% Medicare payment portion as required under Budget Control Act of 2011.
** ASP-based Medicare payment rate not yet available; payment rate assigned by your Medicare Administrative Contractor.

Log in to BioSupply for Immune Globulin Products


FFF customers may order the following complementary resources to help you with your practice:

Seasonal Flu Poster flu myths and facts brochure
immune globulin reference charts
•  IG Immune Globulin (Human)
•  Hyperimmune Globulins
•  Anti-Inhibitor, Factor VIIa & IX
•  Factor VIII & von Willebrand Factor
•  Seasonal Influenza Vaccine

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