SERPINS are inhibitors of serine proteinase found in plasma that target specific serine proteinases involved in coagulation, complement activation, fibrinolysis and inflammation.

Berinert, human plasma-derived, purified, pasteurized concentrate of the protein C1 esterase inhibitor, is specifically indicated for the treatment of acute facial or abdominal attacks of hereditary angioedema (HAE) in adult and adolescent patients.

Thrombate III, a preparation of antithrombin concentrate purified from human plasma, is indicated for the treatment of patients with hereditary antithrombin deficiency in connection with surgical or obstetrical procedures or when they suffer from thromboembolism.